In Vivo Hippocampal Subfield Volumes in Schizophrenia and Bipolar Disorder
نویسندگان
چکیده
منابع مشابه
Comparison of hippocampal volumes in schizophrenia, schizoaffective and bipolar disorder.
The reduction of hippocampal volume was frequently reported in schizophrenia, but not in bipolar disorder This volume reduction is associated with clinical features of schizophrenia, in particular with working and verbal memory impairments. Schizoaffective disorder, as a specific disorder sharing clinical features of both schizophrenia and bipolar disorder is rarely analyzed as a separate disor...
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BACKGROUND Reduced hippocampal volume in schizophrenia is a well-replicated finding. New imaging techniques allow delineation of hippocampal subfield volumes. Studies including predominantly chronic patients demonstrate differences between subfields in sensitivity to illness, and in associations with clinical features. We carried out a cross-sectional and longitudinal study of first episode, su...
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Relative to healthy controls, lithium free bipolar patients exhibit significant gray matter abnormalities. Lithium, the long-time reference standard medication treatment for bipolar disorder, has been proposed to be neuro-protective against these abnormalities. However, its effects on cortical thickness and hippocampal subfield (HSF) volumes remain unstudied and unclear, respectively, in bipola...
متن کاملHippocampal function in schizophrenia and bipolar disorder.
BACKGROUND The hippocampus plays a central role in memory formation. There is considerable evidence of abnormalities in hippocampal structure and function in schizophrenia, which may differentiate it from bipolar disorder. However, no previous studies have compared hippocampal activation in schizophrenia and bipolar disorder directly. METHOD Fifteen patients with schizophrenia, 14 patients wi...
متن کاملCortical thickness and subcortical volumes in schizophrenia and bipolar disorder.
BACKGROUND Schizophrenia and bipolar disorder are severe psychiatric diseases with overlapping symptomatology. Widespread brain morphologic abnormalities, including cortical thinning and subcortical volume reductions, have been demonstrated in schizophrenia but it is unclear whether similar abnormalities are present in bipolar disorder. The purpose of this study was to compare cortical thicknes...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 2015
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2014.06.020